Weight Change Pattern and Survival Outcome of Women with Endometrial Cancer

Weight change and risk of endometrial cancer.

BACKGROUND Obesity is an established risk factor for endometrial cancer. Less well understood is the role of weight gain and weight change in determining risk. METHODS We analysed data from a population-based case-control study to evaluate the associations of body mass index (BMI), weight gain, and weight cycling with risk of endometrial cancer. Cases (n=740) under age 80 with a new diagnosis...

Interventions for weight reduction in obesity to improve survival in women with endometrial cancer.

BACKGROUND Diagnoses of endometrial cancer are increasing secondary to the rising prevalence of obesity. Obesity plays an important role in promoting the development of endometrial cancer, by inducing a state of unopposed oestrogen excess, insulin resistance and inflammation. It also affects treatment, increasing the risk of surgical complications and the complexity of radiotherapy planning, an...

Endometrial cancer in Thai women: clinico-pathological presentation and survival.

OBJECTIVE To assess the characteristic features, treatment, survival, and prognostic factors of Thai endometrial cancer (EMC) patients. METHODS Clinico-pathological data of EMC patients who were treated in the institution from 1992 to 2008 were collected. Survival rates and prognostic factors were studied. RESULTS The mean age of the 261 patients was 55.4 ± 9.92 years. The most common compl...

Endometrial Cancer in Obese Women Endometrial Cancer in Obese Women

Survival of women with clear cell and papillary serous endometrial cancer after adjuvant radiotherapy

BACKGROUND Type II (papillary serous and clear cell) endometrial carcinoma (EC) is a rare subgroup and is considered to have an unfavorable prognosis. The purpose of this retrospective analysis was to elucidate the meaning of adjuvant radiotherapy (RT) for clinical outcome and to define prognostic factors in these patients (pts). METHODS From 2004-2012 forty-two pts with type II EC underwent ...